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Unit­ed Air­lines on Fri­day began oper­at­ing char­ter flights to move ship­ments of Pfiz­er’s COVID-19 vac­ci­na­tion ahead of a mass inoc­u­la­tion pro­gram expect­ed to begin in late Decem­ber, accord­ing to a report.

The flights are the first step in a glob­al sup­ply and dis­tri­b­u­tion net­work, which is being pre­pared to spring into action when the vac­cine is approved by regulators.

The air­line has been grant­ed spe­cial per­mis­sion by the Fed­er­al Avi­a­tion Author­i­ty (FAA) to fly with increased quan­ti­ties of dry ice, to keep the vac­cine cold.